Obesity-Induced Metabolic Changes in Dogs: Mechanisms and Clinical Relevance

Chetna Mahajan; Tanmay Mondal; Pallavi Khajuria; Rachana Sharma and Ravindra Kumar

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Online Published: 17 Oct 2025

IJLSAS. 2025; 7(3): 110-121

Obesity-Induced Metabolic Changes in Dogs: Mechanisms and Clinical Relevance

Chetna Mahajan, Tanmay Mondal, Pallavi Khajuria, Rachana Sharma And Ravindra Kumar.

Abstract
Obesity in dogs has become a global concern, largely as a result of reduced physical activity and excess caloric intake. This condition is associated with numerous metabolic changes, including alterations in glucose and lipid homeostasis, hormonal disruptions, impaired liver function, persistent low-grade inflammation, and increased oxidative stress. This concise review presents up-to-date research on the metabolic consequences of canine obesity, with a focus on their implications for clinical practice and the identification of early markers of metabolic dysfunction. Special attention is given to the processes involved in insulin resistance, disordered adipokine signaling, hepatic fat accumulation, and the growing recognition of the gut microbiome’s role in obesity. Understanding these mechanisms is crucial for prompt detection and for developing evidence-based approaches to prevent and treat obesity in the canine population.

Key words: Obesity, Dogs, Metabolism, Insulin resistance, Dyslipidemia, Adipokines, Hepatic steatosis

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How to Cite this Article

Pubmed Style

Mahajan C, Mondal T, Khajuria P, Kumar RSAR. Obesity-Induced Metabolic Changes in Dogs: Mechanisms and Clinical Relevance. IJLSAS. 2025; 7(3): 110-121.

Web Style

Mahajan C, Mondal T, Khajuria P, Kumar RSAR. Obesity-Induced Metabolic Changes in Dogs: Mechanisms and Clinical Relevance. https://www.ijlsas.com/?mno=290878 [Access: October 17, 2025].

AMA (American Medical Association) Style

Mahajan C, Mondal T, Khajuria P, Kumar RSAR. Obesity-Induced Metabolic Changes in Dogs: Mechanisms and Clinical Relevance. IJLSAS. 2025; 7(3): 110-121.

Vancouver/ICMJE Style

Mahajan C, Mondal T, Khajuria P, Kumar RSAR. Obesity-Induced Metabolic Changes in Dogs: Mechanisms and Clinical Relevance. IJLSAS. (2025), [cited October 17, 2025]; 7(3): 110-121.

Harvard Style

Mahajan, C., Mondal, . T., Khajuria, . P. & Kumar, . R. S. A. R. (2025) Obesity-Induced Metabolic Changes in Dogs: Mechanisms and Clinical Relevance. IJLSAS, 7 (3), 110-121.

Turabian Style

Mahajan, Chetna, Tanmay Mondal, Pallavi Khajuria, and Rachana Sharma And Ravindra Kumar. 2025. Obesity-Induced Metabolic Changes in Dogs: Mechanisms and Clinical Relevance. International Journal Of Life Sciences and Applied Sciences, 7 (3), 110-121.

Chicago Style

Mahajan, Chetna, Tanmay Mondal, Pallavi Khajuria, and Rachana Sharma And Ravindra Kumar. "Obesity-Induced Metabolic Changes in Dogs: Mechanisms and Clinical Relevance." International Journal Of Life Sciences and Applied Sciences 7 (2025), 110-121.

MLA (The Modern Language Association) Style

APA (American Psychological Association) Style

Mahajan, C., Mondal, . T., Khajuria, . P. & Kumar, . R. S. A. R. (2025) Obesity-Induced Metabolic Changes in Dogs: Mechanisms and Clinical Relevance. International Journal Of Life Sciences and Applied Sciences, 7 (3), 110-121.

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